Veratrone—With Special Reference to a Case of Severe Reaction
نویسنده
چکیده
Veratrone is prepared from veratrum viride. It is described as being an aseptic, non-alcoholic, physiologically standardised preparation. Each cubic centimetre represents 0-25 gram, of the drug. It is standardised to a definite degree of activity by physiological tests. It contains a small proportion of chloretone, which acts as a preservative. The patient should always be kept in the recumbent position when this drug is employed. It is suitable both for hypodermic and for oral administration, the former method leading to more prompt physiological action than the latter. The dose is stated to be 0-5 to i-o c.c. hypodermically, followed at short intervals by doses of 0-25 c.c., until the pulse rate is reduced to nearly normal. It is further stated by the makers, Messrs Parke, Davis & Co., that it brings down temperature and causes diaphoresis and diuresis, also that it tends to control convulsions and to eliminate the toxic materials to which they are due. It is also stated that the fall in pulse rate may be so rapid that it may cause some alarm, in which case a hypodermic injection of strychnine may be given. Jardine,1 in referring to cases of eclampsia treated by veratrone, mentions a case of such severe depression that
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